Paper-based microfluidic platforms for osteoporosis diagnosis

Yerrapragada, M.R. and Unni, Harikrishnan Narayanan (2020) Paper-based microfluidic platforms for osteoporosis diagnosis. 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. pp. 1451-1452.

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Abstract

We report a low-cost paper-based diagnostic device (Microfluidic paper based analytic device or muPAD) for diagnosing the biochemical risk factors associated with the onset of Osteoporosis. Photolithography is used to pattern the paper with hydrophilic channels and hydrophobic walls. Briefly, the analytes (serum Calcium and Alkaline Phosphatase) are measured by placing a drop of blood on the sample zone in the device. The serum flows to the test zones containing the immobilized reagents and produces a color reaction. The responses are then compared with the controls and the shift in analyte values from normal indicate normal or diseased state.

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IITH Creators:
IITH CreatorsORCiD
Yerrapragada, M.R.UNSPECIFIED
Unni, Harikrishnan NarayananUNSPECIFIED
Item Type: Article
Uncontrolled Keywords: ALkaline phosphatase; Diagnostic device; Hydrophilic channels; Hydrophobic wall; Immobilized reagents; MuPAD; Osteoporosis; Paper-based microfluidics
Subjects: Biomedical Engineering
Divisions: Department of Biomedical Engineering
Depositing User: . LibTrainee 2021
Date Deposited: 30 Jul 2021 05:55
Last Modified: 30 Jul 2021 05:55
URI: http://raiithold.iith.ac.in/id/eprint/8543
Publisher URL:
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