Palladium-mediated highly regio- and stereoselective intermolecular β-arylation on allylic alcohols: Synthesis of functionalized allylic alcohols

J, Krishna and A, Gopi Krishna Reddy and B, Venkat Ramulu and L, Mahendar and G, Satyanarayana (2012) Palladium-mediated highly regio- and stereoselective intermolecular β-arylation on allylic alcohols: Synthesis of functionalized allylic alcohols. Synlett, 3. pp. 375-380. ISSN 0936-5214

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Abstract

An efficient and highly regio- and stereoselctive Pd-catalyzed β-arylation method for the formation of β-aryl allylic alcohols, employing aryl iodides, 1-bromo-2-iodobenzenes, and 2-bromobezaldehydes as coupling partners, is presented. The β-aryl allylic alcohols formed in this Pd-catalyzed transformation is unexpected under conventional Jeffery conditions without the assistance of silver salt. It is proposed that the reaction is substrate controlled, and the selective formation of the product depends on the size or nature of the substituent at the ortho position on the aromatic ring of the allylic alcohol part

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IITH Creators:	IITH Creators ORCiD G, Satyanarayana UNSPECIFIED
Item Type:	Article
Uncontrolled Keywords:	β-arylation; β-carbonyls; Allylic alcohols; Mizoroki-Heck; Pd catalysis
Subjects:	?? sub5.8 ??
Divisions:	Department of Chemistry
Depositing User:	Team Library
Date Deposited:	17 Nov 2014 05:51
Last Modified:	28 Dec 2015 09:07
URI:	http://raiithold.iith.ac.in/id/eprint/825
Publisher URL:	http://dx.doi.org/10.1055/s-0031-1290203
OA policy:	http://www.sherpa.ac.uk/romeo/issn/0936-5214/
Related URLs:	Google Scholar

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