Oxidative treatment of crude pharmaceutical industry effluent by hydrodynamic cavitation

Lalwani, Jitesh and Gupta, Ashutosh and Thatikonda, Shashidhar and Ch, Subrahmanyam (2020) Oxidative treatment of crude pharmaceutical industry effluent by hydrodynamic cavitation. Journal of Environmental Chemical Engineering, 8 (5). p. 104281. ISSN 22133437

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Abstract

The present study investigates the oxidative technique of hydrodynamic cavitation (HC) for the treatment of a highly refractive, bulk drug industry effluent with an initial total organic carbon (TOC) content of 69960 mg/l. A qualitative insight into the pharmaceutical industry, drug production, and effluent characteristics is presented. Experiments on the undiluted effluent were conducted in accordance with central composite design (CCD). For the venturi-based HC studies, variation of pH (3.63-10.36), inlet pressure (2.95-13.04 bar), and treatment time (26.36-93.63 min.) were studied, besides investigating their effects on treatment efficiency. HC treatment yielded a maximum 25% reduction in TOC with a cavitational yield of 65.69 × 10-3 mg/J for an optimum combination of pH 7, inlet pressure 8 bar, cavitation number of 0.242, and treatment time 60 minutes (17 recirculations). Furthermore, synergetic effects of increasing inlet pressure and effluent temperature were quantified, and found to effectuate a maximum increase of 1781% in vapour pressure, and decrease of 77% in cavitation number. Lastly, effects of operating factors on treatment efficacy and the success of HC system were summarized.

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IITH Creators:

IITH Creators	ORCiD
Lalwani, Jitesh	UNSPECIFIED
Gupta, Ashutosh	UNSPECIFIED
Thatikonda, Shashidhar	https://orcid.org/0000-0003-2973-2224
Ch, Subrahmanyam	https://orcid.org/0000-0002-2643-3854

Item Type:

Article

Uncontrolled Keywords:

Central composite designs; Hydrodynamic cavitations; Optimum combination; Oxidative treatment; Pharmaceutical industry; Synergetic effect; Total Organic Carbon; Treatment efficiency

Subjects:

Chemistry
Chemistry > Inorganic chemistry
Chemical Engineering
Chemical Engineering > Technology of industrial chemicals

Divisions:

Department of Chemistry

Depositing User:

. LibTrainee 2021

Date Deposited:

19 Jun 2021 04:22

Last Modified:

19 Jun 2021 04:22

URI:

http://raiithold.iith.ac.in/id/eprint/7940