Palladium-mediated intramolecular Buchwald-Hartwig α-arylation of β-amino esters: Synthesis of functionalized tetrahydroisoquinolines

Reddy, A G K and Krishna, J and G, Satyanarayana (2011) Palladium-mediated intramolecular Buchwald-Hartwig α-arylation of β-amino esters: Synthesis of functionalized tetrahydroisoquinolines. Synlett, 12. pp. 1756-1760. ISSN 0936-5214

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Abstract

A concise and efficient three-step strategy for the synthesis of functionalized 1,2,3,4-tetrahydroisoquinolines based on an intramolecular Buchwald-Hartwig α-arylation of β-amino esters is described. The synthesis presented is operationally simple and is amenable for the synthesis of a number of analogues.

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IITH Creators:	IITH Creators ORCiD G, Satyanarayana UNSPECIFIED
Item Type:	Article
Uncontrolled Keywords:	-arylation; natural products; palladium catalysis; tetrahydroisoquinolines
Subjects:	?? sub5.8 ??
Divisions:	Department of Chemistry
Depositing User:	Team Library
Date Deposited:	30 Oct 2014 09:58
Last Modified:	24 Sep 2015 10:31
URI:	http://raiithold.iith.ac.in/id/eprint/563
Publisher URL:	http://dx.doi.org/10.1055/s-0030-1260934
OA policy:	http://www.sherpa.ac.uk/romeo/issn/0936-5214/
Related URLs:	Google Scholar

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