Domino [Pd]-Catalysis: One-pot Synthesis of Isobenzofuran-1(3H)-ones

Lodi, M and G, Satyanarayana (2016) Domino [Pd]-Catalysis: One-pot Synthesis of Isobenzofuran-1(3H)-ones. Journal of Organic Chemistry, 81 (17). pp. 7685-7691. ISSN 0022-3263

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Abstract

An efficient domino [Pd]-catalysis for the synthesis of isobenzofuran-1(3H)-ones, is presented. The strategy showed broad substrate scope and amenable to ortho-bromobenzyl tertiary/secondary/primary alcohols. Significantly, the method was applied to the synthesis of anti-platelet drug n-butyl phthalide and cytotoxic agonist 3a-[4’-methoxylbenzyl]-5,7-dimethoxyphthalide.

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IITH Creators:	IITH Creators ORCiD G, Satyanarayana UNSPECIFIED
Item Type:	Article
Subjects:	Chemistry > Organic chemistry ?? sub5.8 ??
Divisions:	Department of Chemistry
Depositing User:	Team Library
Date Deposited:	16 Aug 2016 08:40
Last Modified:	03 Oct 2016 06:08
URI:	http://raiithold.iith.ac.in/id/eprint/2636
Publisher URL:	http://dx.doi.org/10.1021/acs.joc.6b01396
OA policy:	http://www.sherpa.ac.uk/romeo/issn/0022-3263/
Related URLs:	Google Scholar

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