Shiraj, Abdul and Khan, Faiz Ahmed
(2016)
A Facile Synthesis of Chiral β-substituted α-Amino Ester Analogue of Indenone via Addition Elimination Reaction.
Masters thesis, Indian Institute of Technology Hyderabad.
Abstract
Indenone core is a very important pharmacophore in organic chemistry. α‚ β substituted chloro or bromo indenones easily undergo addition-elimination reaction with suitable nucleophile like α-amino esters and produce the corresponding chiral β substituted α -amino ester analogue of indenone in an impressive yield. The reaction can be performed in a mild condition without any catalyst‚ base or acid. Thus formation of C-N bond is possible in this type of reaction in a catalyst free mild condition.
[error in script]
| IITH Creators: |
| IITH Creators | ORCiD |
|---|
| Khan, Faiz Ahmed | UNSPECIFIED |
|
| Item Type: |
Thesis
(Masters)
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| Uncontrolled Keywords: |
Pharmacophore, chiral pool, TD545 |
| Subjects: |
Chemistry |
| Divisions: |
Department of Chemistry |
| Depositing User: |
Library Staff
|
| Date Deposited: |
24 Jun 2016 05:58 |
| Last Modified: |
22 May 2019 05:12 |
| URI: |
http://raiithold.iith.ac.in/id/eprint/2475 |
| Publisher URL: |
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| Related URLs: |
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