Atrial Fibrillation: Biophysics, Molecular Mechanisms, and Novel Therapies

Glukhov, A V and Rosenshtraukh, L V and Bhargava, Anamika and Miragoli, M and Boukens, B J D (2015) Atrial Fibrillation: Biophysics, Molecular Mechanisms, and Novel Therapies. BioMed Research International, 2015 (780671). pp. 1-2. ISSN 2314-6133

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Abstract

Atrial fibrillation (AF) affects millions of people worldwide and is associated with increased morbidity and mortality [1]. The incidence of AF is expected to rise with aging of the population. Research over the past decades has identified a multitude of pathophysiological processes contributing to the initiation, maintenance, and progression of AF. Therefore, a comprehensive understanding of AF pathophysiology is needed to foster the development of improved diagnostic, pharmacological, and nonpharmacological therapeutic approaches to improve clinical management. The focus of this special issue of this journal is to capture most recent advances in the study of AF with the aim of directing further research. Conventional mechanisms linked to AF are diverse and expertly reviewed in various manuscripts [2, 3]. However, progression in the field of AF research may come from an unconventional view-angle. For example, M. Miragoli and A. V. Glukhov reviewed the role of myofibroblasts as novel targets for cardiac arrhythmias with the aim of describing and evaluating the implications of noncardiomyocyte view in the context of AF. B. Weil and C. Ozcan discussed the pathophysiological remodelling in AF in comparison with that occurring in hibernating myocardium, attempting to identify common molecular mechanisms and proposing possible future therapeutic implications of this emerging paradigm.

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IITH Creators:

IITH Creators	ORCiD
Bhargava, Anamika	http://orcid.org/0000-0002-1048-3427

Item Type:

Article

Additional Information:

As the guest editors of this special issue we would like to acknowledge all authors and reviewers who contributed either by reviewing recent literature or by including original experimental and clinical studies, making this issue valuable for diverse audience of researchers interested in the AF pathophysiology and therapy.

Subjects:

Others > Biotechnology

Divisions:

Department of Biotechnology

Depositing User:

Team Library

Date Deposited:

11 Aug 2015 10:49

Last Modified:

29 Aug 2017 11:30

URI:

http://raiithold.iith.ac.in/id/eprint/1847