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Article

Bharathi, Vidhya and Bajpai, Akarsh and Patel, Basant Kumar and et al, . (2022) Elevated constitutive expression of Hsp40 chaperone Sis1 reduces TDP-43 aggregation-induced oxidative stress in Ire1 pathway dependent-manner in yeast TDP-43 proteinopathy model of amyotrophic lateral sclerosis. Biochemical and Biophysical Research Communications, 595. pp. 28-34. ISSN 0006-291X

Nirwal, S. and Patel, B.K. and et al, . (2021) Amyloid-like aggregation of bovine serum albumin at physiological temperature induced by cross-seeding effect of HEWL amyloid aggregates. Biophysical Chemistry, 278. p. 106678. ISSN 0301-4622

Bharathi, V. and Manglunia, R.R. and Sharma, N. and Nirwal, S. and Patel, Basant Kumar (2021) Pharmaceutical acetylation can modulate the amyloidogenicity of human serum albumin. Indian Journal of Biochemistry and Biophysics, 58 (4). pp. 344-351. ISSN 0301-1208

Bharathi, V. and Patel, B. K. and et al, . (2021) Role of CNC1 gene in TDP-43 aggregation-induced oxidative stress-mediated cell death in S. cerevisiae model of ALS. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1868 (6). p. 118993. ISSN 01674889

Preethi, S and Bharathi, Vidhya and Patel, Basant Kumar (2021) Zn2+ modulates in vitro phase separation of TDP-432C and mutant TDP-432C-A315T C-terminal fragments of TDP-43 protein implicated in ALS and FTLD-TDP diseases. International Journal of Biological Macromolecules, 176. pp. 186-200. ISSN 0141-8130

Bharathi, Vidhya and Girdhar, Amandeep and Patel, Basant Kumar (2020) Role of CNC1 gene in TDP-43 aggregation-induced oxidative stress-mediated cell death in S. cerevisiae model of AL. Bioarxiv.

Girdhar, Amandeep and Bharathi, Vidhya and Patel, Basant Kumar and et al, . (2019) Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4. bioRxiv.org.

Prasad, A. and Patel, B. K. and et al, . (2019) Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis. Frontiers. ISSN 0160-9009

Verma, Meenakshi and Girdhar, Amandeep and Patel, Basant Kumar and Ganguly, Nirmal K and Kukreti, Ritushree and Taneja, Vibha (2018) Q-Rich Yeast Prion [PSI+] Accelerates Aggregation of Transthyretin, a Non-Q-Rich Human Protein. Frontiers in Molecular Neuroscience, 11. ISSN 1662-5099

Prasad, Archana and Sivalingam, Vishwanath and Bharathi, Vidhya and Girdhar, Amandeep and Patel, Basant Kumar (2018) The amyloidogenicity of a C-terminal region of TDP-43 implicated in Amyotrophic Lateral Sclerosis can be affected by anions, acetylation and homodimerization. Biochimie. ISSN 0300-9084 (In Press)

Serio, T R and Park, S-K and Hong, J Y and Arslan, F and Kanneganti, V and Patel, Basant Kumar and Tietsort, A and Tank, E M H and Li, X and Barmada, S J and Liebman, S W (2017) Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis. PLOS Genetics, 13 (5). e1006805. ISSN 1553-7404

Bharathi, V and Girdhar, A and Patel, Basant Kumar (2017) A Protocol of Using White/Red Color Assay to Measure Amyloid-induced Oxidative Stress in Saccharomyces cerevisiae. Bio-Protocol, 7 (15). ISSN 2331-8325

Sivalingam, V and Patel, Basant Kumar (2016) Familial mutations in fibrinogen Aα (FGA) chain identified in renal amyloidosis increase in vitro amyloidogenicity of FGA fragment. Biochimie, 127. pp. 44-49. ISSN 0300-9084

Gembali, R and S, Vishwanath and Prasad, A and Patel, Basant Kumar and G, Prabusankar (2016) Imidazolium tagged acridines: Synthesis, characterization and applications in DNA binding and anti-microbial activities. Journal of Molecular Structure, 1107. pp. 291-299. ISSN 0022-2860

Sharma, N and Vishwanath, S and Patel, Basant Kumar (2016) Recombinant Human Semenogelin-1 (Sg1) and Sg1 (1-159) form Detergent Stable Amyloid like Aggregates in vitro. Protein and Peptide Letters, 23 (1). pp. 87-96. ISSN 0929-8665

Bharathi, V and Giridhar, A and Prasad, A and Verma, M and Taneja, V and Patel, Basant Kumar (2016) Use of ade1 and ade2 mutations for development of a versatile red/white colour assay of amyloid-induced oxidative stress in saccharomyces cerevisiae. Yeast, 33 (12). pp. 607-620. ISSN 0749-503X

Bharathi, V and Girdhar, A and Prasad, A and Verma, M and Taneja, V and Patel, Basant Kumar (2016) Use ofade1andade2mutations for development of a versatile red/white colour assay of amyloid-induced oxidative stress insaccharomyces cerevisiae. Yeast. ISSN 0749-503X (In Press)

Sivalingam, V and Prasanna, N L and Sharma, N and Prasad, A and Patel, Basant Kumar (2016) Wild-type hen egg white lysozyme aggregation in vitro can form self-seeding amyloid conformational variants. Biophysical Chemistry, 219. pp. 28-37. ISSN 0301-4622

Prasad, A and Raju, G and Sivalingam, V and Girdhar, A and Verma, M and Vats, A and Taneja, V and G, Prabusankar and Patel, Basant Kumar (2016) An acridine derivative, [4,5-bis{(N-carboxy methyl imidazolium)methyl}acridine] dibromide, shows anti-TDP-43 aggregation effect in ALS disease models. Scientific Reports, 6 (39490). pp. 1-14. ISSN 2045-2322

Sharma, N and Vishwanath, S and Maurya, S and Prasad, A and Khandelwal, P and Yadav, S C and Patel, Basant Kumar (2015) New insights into in vitro amyloidogenic properties of human serum albumin suggest considerations for therapeutic precautions. FEBS Letters, 589 (24P-B). pp. 4033-4038. ISSN 0014-5793

Patel, Basant Kumar and Medicherla, V J (2010) Structural Insights of the Cysteine Protease Heynein from Induction and Characterization of Non-native Intermediate States. Journal of Proteins and Proteomics, 1 (2). pp. 43-51. ISSN 0975-8151

Thesis

Girdhar, Amandeep and Patel, Basant Kumar (2020) Investigation of role of TDP-43 aggregation on heterologous aggregating proteins and modulation of TDP-43 aggregation by small molecules. PhD thesis, Indian Institute of Technology Hyderabad.

S, Preethi and Patel, Basant Kumar (2019) Effect of Zinc on the in vitro aggregation and phase separation of TDP-43 protein implicated in Amyotrophic Lateral Sclerosis. Masters thesis, Indian institute of technology Hyderabad.

Parappuram, Irene Tomy and Patel, Basant Kumar (2019) The role of ER stress genes in modulating the toxicity of TDP43 in yeast ALS model. Masters thesis, Indian institute of technology Hyderabad.

S, Jeevotham and Patel, Basant Kumar (2018) Average Distance Map Analysis of Amyloidogenic Protein Domains. Masters thesis, Indian Institute of Technology Hyderabad.

Prasad, Archana and Patel, Basant Kumar (2017) Protein misfolding studies on TDP-43 protein involved in Amyotrophic Lateral Sclerosis (ALS) disease. PhD thesis, Indian institute of technology Hyderabad.

Sivalingam, Vishwanath and Patel, Basant Kumar (2017) Protein misfolding studies on human fibrinogen alpha chain and hen egg white lysozyme. PhD thesis, Indian institute of technology Hyderabad.

B, Tirumaleshwar Reddy and Patel, Basant Kumar (2015) Finding Universal Inhibitor of Amyloid Aggregation. Masters thesis, Indian Institute of Technology Hyderabad.

Other

Patel, Basant Kumar and Singh, Sandeep K and Eerappa, Rajakumara and et al, . (2020) IIT Hyderabad finds better solution to treat 'Lou Gehrig's disease. India Today, Hyderabad.