Ascorbic acid assisted synthesis of fluorescent PEG for bioimaging application

Mudigunda, Sushma V. and Ravichandran, Gayathri and Appidi, Tejaswini and Rengan, Aravind Kumar (2022) Ascorbic acid assisted synthesis of fluorescent PEG for bioimaging application. Materials Today: Proceedings, 62. pp. 5189-5193. ISSN 2214-7853

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Abstract

Highly fluorescent Polyethylene glycol (PEG) was synthesized with the incorporation of ascorbic acid. With a facile synthesis induced by heating, PEG molecule was furnished with its fluorescent property along with its ingrained virtues of being biocompatible and biodegradable. The ascorbic acid modified PEG (FLPEG AA) demonstrated a red shift in the fluorescence and further optimization with the ascorbic acid concentration in the system, highly fluorescent nanoparticles were elicited for the application of cancer cell imaging. In addition, with the preliminary studies, we attempted to deduce the effect of different types of materials such as polymers (PVP) and metals (Gold NPs) towards the fluorescence property of the PEG AA. © 2022

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IITH Creators:

IITH Creators	ORCiD
Rengan, Aravind Kumar	https://orcid.org/0000-0003-3994-6760

Item Type:

Article

Additional Information:

The authors thank the Department of Science & Technology (DST), the Department of Biotechnology (DBT), the Ministry of Human Resources & Development (MHRD), Government of India, for funding the following projects: DST-Inspire (DST/INSPIRE/04/2015/000377), DBTNNT(BT/NNT/28/1386/2017), DST-AMT(DST/TDT/AMT/2017/227(G)), & MHRD IMPRINT (4291). Authors G.R., and S.M., thank MHRD for providing a fellowship. Author T.A. thank the DST for an Inspire fellowship (IF160291).

Uncontrolled Keywords:

Ascorbic acid modified fluorescent PEG (FL PEG AA); Fluorescence; Fluorescent PEG (FL PEG); Imaging; Polyethylene glycol (PEG); Polyvinylpyrrolidone (PVP)

Subjects:

Biomedical Engineering

Divisions:

Department of Biomedical Engineering

Depositing User:

. LibTrainee 2021

Date Deposited:

22 Jul 2022 12:04

Last Modified:

22 Jul 2022 12:04

URI:

http://raiithold.iith.ac.in/id/eprint/9873