Alkali and Alkaline Earth Metal Complexes as Versatile Catalysts for Ring-Opening Polymerization of Cyclic Esters

Bhattacharjee, J. and Panda, Tarun K and et al, . (2021) Alkali and Alkaline Earth Metal Complexes as Versatile Catalysts for Ring-Opening Polymerization of Cyclic Esters. The Chemical Record, 21 (8). pp. 1898-1911. ISSN 1527-8999

Text
TKP-Preprint-124.pdf
Download (1MB)

Abstract

Biodegradable polyesters such as poly(ϵ-caprolactone) (PCL) and poly(lactic acid) (PLA) have been considered for use in several areas, such as drug delivery devices, sutures, tissue engineering, and GBR membranes, due to its bio-renewability, biodegradability, and biocompatibility. Several synthetic techniques for the preparation of polyesters have been reported in the literature, amongst which the ring-opening polymerization (ROP) of cyclic esters is the most efficient. A convenient approach to access iso-selective PLAs is polymerization of racemic lactide (rac-LA), which shows excellent stereoregularity without the need for costly chiral auxiliaries or ligands. In this personal account, we review a series of methods that have been practiced to the synthesis of biodegradable polyesters from various cyclic monomers using alkali and alkaline earth metal complexes as efficient catalysts.

[error in script]

IITH Creators: