Role of nano-sensitizers in radiation therapy of metastatic tumors

Thanekar, Ajinkya Madhukar and Sankaranarayanan, Sri Amruthaa and Rengan, Aravind Kumar (2021) Role of nano-sensitizers in radiation therapy of metastatic tumors. Cancer Treatment and Research Communications, 26. p. 100303. ISSN 24682942

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Abstract

Cancer metastasis remains the major cause of global cancer deaths. Radiation therapy remains one of the golden standards for cancer treatment. Nanomedicine based strategies have been designed and developed in order to improve the clinical outcomes of cancer therapy and diagnosis at molecular levels. Over the years, several researchers have shown their interest in using radiosensitizers made of high Z elements. Metal-based nanosystems also play a dual role by enhancing the synergistic effect of cell killing via various biological immune responses. This review summarizes the role of Nano-sensitizers in boosting radiation (ionizing/non-ionizing radiations) induced biological responses in treatment of metastatic cancer models.

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IITH Creators:	IITH Creators ORCiD Thanekar, Ajinkya Madhukar UNSPECIFIED Sankaranarayanan, Sri Amruthaa UNSPECIFIED Rengan, Aravind Kumar UNSPECIFIED
Item Type:	Article
Uncontrolled Keywords:	Abscopal effect; Cancer metastasis; Nanomedicine; Radiation therapy; Radiosensitizers
Subjects:	Biomedical Engineering
Divisions:	Department of Biomedical Engineering
Depositing User:	. LibTrainee 2021
Date Deposited:	23 Sep 2021 10:31
Last Modified:	23 Sep 2021 10:31
URI:	http://raiithold.iith.ac.in/id/eprint/8849
Publisher URL:	http://doi.org/10.1016/j.ctarc.2021.100303
Related URLs:	Author

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