Detection of bovine serum albumin using hybrid TiO2 + graphene oxide based Bio – resistive random access memory device

Sahu, Dwipak Prasad and Jammalamadaka, S Narayana (2019) Detection of bovine serum albumin using hybrid TiO2 + graphene oxide based Bio – resistive random access memory device. Scientific Reports, 9 (1). ISSN 2045-2322

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Abstract

Bio – molecules detection and their quantifcation with a high precision is essential in modern era of medical diagnostics. In this context, the memristor device which can change its resistance state is a promising technique to sense the bio - molecules. In this work, detection of the Bovine Serum Albumin (BSA) protein using resistive switching memristors based on TiO2 and TiO2+graphene oxide (GO) is explored. The sensitivity of BSA detection is found to be 4mg/mL. Both the devices show an excellent bipolar resistive switching with an on/of ratio of 73 and 100 respectively, which essentially demonstrates that the device with GO, distinguishes the resistance states with a high precision. The enhanced performance in the GO inserted device (~ 650 cycles) is attributed to the prevention of multidimensional and random growth of conductive paths.

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