Microwave-Assisted Domino Palladium Catalysis in Water: A Diverse Synthesis of 3,3′-Disubstituted Heterocyclic Compounds

Ramesh, Karu and Basuli, Suchand and G, Satyanarayana (2018) Microwave-Assisted Domino Palladium Catalysis in Water: A Diverse Synthesis of 3,3′-Disubstituted Heterocyclic Compounds. European Journal of Organic Chemistry, 2018 (19). pp. 2171-2177. ISSN 1434193X

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Abstract

A domino [Pd]‐catalyzed synthesis of 3,3′‐disubstituted indolines, oxindoles, and dihydrobenzofurans is devised under microwave irradiation from readily available starting materials by using water as the sole green solvent. The strategy presents an excellent functional‐group tolerance with broad substrate scope. An environmentally benign microwave‐assisted domino [Pd]‐catalyzed reaction, for the efficient and diverse synthesis of 3,3′‐disubstituted indolines, oxindoles, and dihydrobenzofurans, is presented. Significantly, water served as the sole green solvent and the strategy displayed an excellent functional‐group tolerance. Remarkably, the process was also amenable to unmasked functional groups and furnished the products, in very good to almost quantitative yields.

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IITH Creators:	IITH Creators ORCiD G, Satyanarayana UNSPECIFIED
Item Type:	Article
Uncontrolled Keywords:	Indexed in Scopus and WoS
Subjects:	Chemistry
Divisions:	Department of Chemistry
Depositing User:	Library Staff
Date Deposited:	16 Oct 2019 09:16
Last Modified:	16 Oct 2019 09:16
URI:	http://raiithold.iith.ac.in/id/eprint/6595
Publisher URL:	http://doi.org/10.1002/ejoc.201800155
Related URLs:	Google Scholar

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