Sahu, S and Kumar, G V P and Paul, B and Singh, Riddhi and et al, .
(2018)
Towards Early Detection Of Hypoxia: Fabrication Of Facile, Robust, Cobalt Doped Zno Nano Fiber For In Situ Sensing Of Dissolved Oxygen.
In: EMBS Micro and nanotechnology in medicine conference, 10-14 December 2018, Kauai, Hawaii.
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Abstract
Hypoxia is associated with many diseases, such as cancer, neurodegeneration and diabetes, and this
leads to a demand for in situ oxygen sensing for biomedical applications. Although, in the past, various
metal oxide nanofibers have been used successfully for sensing gaseous oxygen at higher temperature,
sensing gaseous as well as dissolved oxygen at room temperature remains challenging. In this work, we
have developed a common framework for sensing gaseous and dissolved oxygen using metal oxide
nanofibers, and have presented a proof of conecept towards oxygen sensing in aqueous medium. Herein,
we propose oxygen sensing using Co doped ZnO nanofiber and have investigated oxygen sensing
dynamics. Characterization of the fiberes have been performed using scanning electron microscopy. It
has been observed that Co doping yields lower resistance values for the composite nanofiber and hence
improves its sensitivity. In order to obtain hydrophilic surface for sensing dissolved oxygen, we have
perfomed plasma treatment of the nanofibers. In relation to dissolved oxygen sensing, the proposed
sensor accounts for a response time close to 60 seconds. The proposed miniaturized sensor has the
potential for sensing oxygen in body fluid as well as tissue models
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