A simple process for selective bio-functionalization of SU-8 surface for Lab-on-a-Chip applications

Srinivasan, B and Chaurasia, Durgesh and Vanjari, Siva Rama Krishna and Singh, Shiv Govind (2015) A simple process for selective bio-functionalization of SU-8 surface for Lab-on-a-Chip applications. In: TechConnect World Innovation, 15-17 June 2015, Washington , DC.

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Abstract

SU-8 is a popular epoxy based negative photoresist developed by IBM. It has been widely used as structural material in Bio-MEMS and Lab-on-a-Chip devices due to its bio-compatible properties. SU-8 surface has hydrophobic nature. Often it is made to be hydrophilic for microfluidic transport and bio-functionalization purposes. Selective functionalization and permanent hydrophilicity are most desired for Lab-on-a-Chip application and increased shelf life of devices. There are few proven process to achieve a selective and stable hydrophilic SU-8 surfaces. In this work we extend these processes and functionlize the SU-8 surface with Biotin molecules as a proof of concept. The immobilized biotin can be used to detect Avidin and Streptavidin molecules. Relevant surface characterization results would be furnished to prove the process. This simple process has greater potential in manufacturing of Lab-on-a-Chip and Biosensor devices.

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IITH Creators:	IITH Creators ORCiD Singh, Shiv Govind http://orcid.org/0000-0001-7319-879X Vanjari, Siva Rama Krishna UNSPECIFIED
Item Type:	Conference or Workshop Item (Paper)
Subjects:	Electrical Engineering
Divisions:	Department of Electrical Engineering
Depositing User:	Team Library
Date Deposited:	27 Jun 2019 05:26
Last Modified:	27 Jun 2019 05:26
URI:	http://raiithold.iith.ac.in/id/eprint/5568
Publisher URL:
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