Direct Evidence for Microdomain-Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes

Glukhov, Alexey V and Balycheva, Marina and Bhargava, Anamika and Ilkan, Zeki (2015) Direct Evidence for Microdomain-Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes. Circulation, 132 (25). pp. 2372-2384. ISSN 0009-7322

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Abstract

Distinct subpopulations of L-type calcium channels (LTCCs) with different functional properties exist in cardiomyocytes. Disruption of cellular structure may affect LTCC in a microdomain-specific manner and contribute to the pathophysiology of cardiac diseases, especially in cells lacking organized transverse tubules (T-tubules) such as atrial myocytes (AMs).

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IITH Creators:	IITH Creators ORCiD Bhargava, Anamika http://orcid.org/0000-0002-1048-3427
Item Type:	Article
Subjects:	Others > Biotechnology
Divisions:	Department of Biotechnology
Depositing User:	Team Library
Date Deposited:	31 May 2019 07:58
Last Modified:	31 May 2019 08:00
URI:	http://raiithold.iith.ac.in/id/eprint/5408
Publisher URL:	http://doi.org/10.1161/CIRCULATIONAHA.115.018131
Related URLs:	Google Scholar

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