Debsarma, Shoyan and Khan, Faiz Ahmed
(2019)
Efforts Towards The Total Synthesis Of Dichocetide C.
Masters thesis, Indian institute of technology Hyderabad.
Abstract
The attempts towards the synthesis of the fragments for total synthesis of Dichocetide C has been reported by two retrosynthetic approaches. First retrosynthetic approach involves reduction of aldehyde to alcohol, bromination of alcohol by appel reaction, hydrogenation of alkene bond and organomagnesium, organozinc and organolithium reactions. Second retrosynthesis approach involves one carbon homologation reaction of aldehydes by Wittig reaction followed by hydrolysis, reduction of aldehyde to alcohol, bromination of alcohol and Grignard reaction. Unfortunately the schemes were failed, the synthesis of the retrons is reported.
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| IITH Creators: |
| IITH Creators | ORCiD |
|---|
| Khan, Faiz Ahmed | UNSPECIFIED |
|
| Item Type: |
Thesis
(Masters)
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| Uncontrolled Keywords: |
Total Synthesis, Dichocetide C, Marine Derived Natural Product, Witting Reaction |
| Subjects: |
Chemistry |
| Divisions: |
Department of Chemistry |
| Depositing User: |
Team Library
|
| Date Deposited: |
13 May 2019 06:59 |
| Last Modified: |
13 May 2019 06:59 |
| URI: |
http://raiithold.iith.ac.in/id/eprint/5130 |
| Publisher URL: |
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| Related URLs: |
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