Three-dimensional bioprinting for bone tissue regeneration

Adepu, Shivakalyani and Dhiman, Nandini and Laha, Anindita and Sharma, Chandra Shekhar and Ramakrishna, Seeram and Khandelwal, Mudrika (2017) Three-dimensional bioprinting for bone tissue regeneration. Current Opinion in Biomedical Engineering, 2. pp. 22-28. ISSN 2468-4511

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Abstract

Three-dimensional bioprinting can prove to be a promising technology for bone tissue regeneration as it facilitates good spatio-temporal distribution of cells in scaffold. The feed for bioprinting is bioink, which comprises of cells incorporated in the scaffold material. Progress has been made on the incorporation of growth factors in the bioink, which not only enables efficient regeneration but at the same time proves the feasibility of large constructs. Important parameters which determine the suitability of bioink have been discussed here. Lack of vascularization limits the success of this technology in its present form. Advances in inducing vascularization and growth factors have also been discussed. Towards the end, challenges and opinions in the area of bioprinting of bone tissue regeneration have been presented.

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IITH Creators:	IITH Creators ORCiD Sharma, Chandra Shekhar UNSPECIFIED Khandelwal, Mudrika UNSPECIFIED
Item Type:	Article
Uncontrolled Keywords:	Bioink, Growth factors, Controlled release, Angiogenesis, Osteogenesis
Subjects:	Chemical Engineering
Divisions:	Department of Chemical Engineering
Depositing User:	Team Library
Date Deposited:	14 Dec 2018 03:56
Last Modified:	14 Dec 2018 03:56
URI:	http://raiithold.iith.ac.in/id/eprint/4626
Publisher URL:	http://doi.org/10.1016/j.cobme.2017.03.005
Related URLs:	Google Scholar

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