New biomarkers in brain trauma

Tomar, Gaurav Singh and Singh, Gyaninder Pal and Lahkar, Dhruba and Sengar, Kangana and Nigam, Richa and Mohan, Monisha and Roy, Anindya (2018) New biomarkers in brain trauma. Clinica Chimica Acta, 487. pp. 325-329. ISSN 0009-8981

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Abstract

Brain-specific biomolecules are being increasingly investigated as a viable alternative to the clinical scores and radiological features, on which we still rely upon for stratification, therapy and predicting outcome in traumatic brain injury (TBI). TBI generally leads to release of various chemical compound within the cerebrospinal fluid (CSF) or blood depending on the severity of injury, which were studied variedly in last decades. However, most of these compounds being non-specific to brain, their applicability was challenged further. This review encompasses the novel and promising biomarkers being studied in the present decade, with encouraging results in laboratory and animal or human models.

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IITH Creators:	IITH Creators ORCiD Roy, Anindya http://orcid.org/0000-0001-8561-907X
Item Type:	Article
Uncontrolled Keywords:	Biomarkers, Traumatic brain injury, Cerebrospinal fluid, Serum, UCH-L1
Subjects:	Others > Biotechnology
Divisions:	Department of Biotechnology
Depositing User:	Team Library
Date Deposited:	24 Oct 2018 05:42
Last Modified:	24 Oct 2018 05:42
URI:	http://raiithold.iith.ac.in/id/eprint/4494
Publisher URL:	http://doi.org/10.1016/j.cca.2018.10.025
OA policy:	http://www.sherpa.ac.uk/romeo/issn/0009-8981/
Related URLs:	Google Scholar

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