N -dealkylative S N Ar reaction using aromatic halides: Synthesis of dihydrobenzoxazine and tetrahydrobenzoxazepine derivatives

Pathan, Mosim Amin and Khan, Faiz Ahmed (2017) N -dealkylative S N Ar reaction using aromatic halides: Synthesis of dihydrobenzoxazine and tetrahydrobenzoxazepine derivatives. Tetrahedron, 73 (41). pp. 6008-6020. ISSN 0040-4020

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Abstract

An efficient protocol for the synthesis of dihydrobenzoxazine and tetrahydrobenzoxazepine derivatives has been developed using haloarenes involving N-dealkylative SNAr reaction. The method employs a wide variety of substrates and features the formation of Csingle bondO and Csingle bondN bonds in one-pot fashion. The products thus generated have been further transformed to m-terphenyls by using Suzuki coupling reaction.

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IITH Creators:	IITH Creators ORCiD Khan, Faiz Ahmed UNSPECIFIED
Item Type:	Article
Additional Information:	FAK gratefully acknowledges DBT for financial support. MAP thanks CSIR for the award of a fellowship.
Uncontrolled Keywords:	Dihydrobenzoxazine; Tetrahydrobenzoxazepine; Complementary pairing; Complementary ambiphile pairing; Cyclization
Subjects:	Chemistry
Divisions:	Department of Chemistry
Depositing User:	Team Library
Date Deposited:	05 Sep 2017 09:22
Last Modified:	02 Aug 2018 11:42
URI:	http://raiithold.iith.ac.in/id/eprint/3521
Publisher URL:	https://doi.org/10.1016/j.tet.2017.08.047
OA policy:	http://www.sherpa.ac.uk/romeo/issn/0040-4020/
Related URLs:	Google Scholar

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