Highly Sensitive Electrospun Multiwalled Carbon Nanotubes Embedded Zinc Oxide Nanowire Based Interface for Label Free Biosensing

Paul, K B and Vanjari, Siva Rama Krishna and Singh, Shiv Govind (2017) Highly Sensitive Electrospun Multiwalled Carbon Nanotubes Embedded Zinc Oxide Nanowire Based Interface for Label Free Biosensing. Procedia Technology, 27. pp. 217-218. ISSN 2212-0173

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Abstract

We demonstrate synthesis of Multiwalled carbon nanotubes (MW CNTs) embedded highly oriented Zinc Oxide (ZnO) nanowires targeted towards development of ultrasen sitive electrochemical nanobiosensors using electrospinning method. The synthesized composite nanowires combines advantages of ZnO such as biocompa tibility, electrostatic affinity towards biomolecules with the excellent conductivity and surface functi onalization capabilities of MWCNTs. Calcinatio n temperature is optimized so as to ensure MWCNTs are present in their original form and at the same time highly crystalline ZnO is obtained. The key advantage o f this process is that there is no separate functionalization pr ocess is required to create functional groups on MWCNTs. Furthermore, the electrochemical activity of MWCNTs embedded ZnO nanowires is much higher as compared to pure ZnO nanowires. We have demonstrated the performance of electrochem ical nanobiosensor using Biotin -streptavidin interaction as model system. The sensor exhibits excellent sensitivity in the range 10 μ gmL -1 - 0.5 fgmL -1 of streptavidin with 0.5fgmL -1 limit of detection.

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