Ultrasensitive Nanobiosensor Platform Based on Electrospun Composite Nanofibers

M, Durga Prakash (2016) Ultrasensitive Nanobiosensor Platform Based on Electrospun Composite Nanofibers. PhD thesis, Indian Institute of Technology Hyderabad.

Text
EE10P005.pdf - Submitted Version
Restricted to Registered users only until 17 July 2021.
Download (47MB) | Request a copy

Abstract

The advent of nanotechnology and fabrication has opened up a plethora of ways to design and de- velop point of care diagnostics. These biosensors/devices use several transduction mechanisms, the predominant ones being potentiometric, amperometric, conductometric, cantilever, electrochemical, optical and magnetic transduction mechanisms. Though the principle of transduction mechanism is known, the novelty lies in the ability to engineer the biosensor to achieve very high sensitivity and selectivity. Nanotechnology enabled researchers to design and develop these biosensors whose dimen- sions are in the range of nanometers, thereby exploiting the inherent advantages of nano regime viz, high surface to volume ratio, availability of active sites, chemical/bio functionalization so on and so forth. One of the key parameters to be considered is the economic viability of making nanobiosensors without compromising on the sensitivity.

[error in script]

IITH Creators: