Optimum culture medium composition for rhamnolipid production by pseudomonas aeruginosa AT10 using a novel multi-objective optimization method

Jujjavarapu, S E and Mohan, Anand and Chimmiri, V (2013) Optimum culture medium composition for rhamnolipid production by pseudomonas aeruginosa AT10 using a novel multi-objective optimization method. Journal of Chemical Technology and Biotechnology, 88 (2). pp. 271-279. ISSN 0268-2575

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Abstract

Rhamnolipid is a biosurfactant that finds wide applications in pharmaceuticals and beauty products. Pseudomonas aeruginosa is a producer of rhamnolipids, and the process can be implemented under laboratory-scale conditions. Rhamnolipid concentration depends on medium composition namely, carbon source concentration, nitrogen source concentration, phosphate content and iron content. In this work, existing data7 were used to develop an artificial neural network-based response surface model (ANN RSM) for rhamnolipid production by pseudomonas aeruginosa AT10. This ANN RSM model is integrated with non-dominated sorting differential evolution (DE) to identify the optimum medium composition for this process.

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