Concise Three-Step Strategy for the Synthesis of 2-Benzoxepin-3(1H)-ones

Hazra, M and Jonnada, K and G, Satyanarayana (2015) Concise Three-Step Strategy for the Synthesis of 2-Benzoxepin-3(1H)-ones. Synthesis, 47 (9). pp. 1245-1254. ISSN 0039-7881

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Abstract

A short and efficient method was developed for the synthesis of 2-benzoxepin-3(1H)-ones. The synthetic sequence comprises of initial intermolecular Heck coupling, followed by reduction of the carbonyl functionality of the Heck product and finally base-induced intramolecular condensation. Notably, the final condensation may proceed by an interesting oxy-Michael addition, cycloreversion via double bond isomerization and intramolecular condensation.

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IITH Creators:	IITH Creators ORCiD G, Satyanarayana UNSPECIFIED
Item Type:	Article
Additional Information:	Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0034-1379901.
Uncontrolled Keywords:	palladium catalysis - Heck coupling - reduction - condensation - benzoxepinones
Subjects:	?? sub5.8 ??
Divisions:	Department of Chemistry
Depositing User:	Team Library
Date Deposited:	07 Apr 2015 05:31
Last Modified:	24 Sep 2015 10:18
URI:	http://raiithold.iith.ac.in/id/eprint/1438
Publisher URL:	http://dx.doi.org/10.1055/s-0034-1379901
OA policy:	http://www.sherpa.ac.uk/romeo/issn/0039-7881/
Related URLs:	Google Scholar

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