Methanol as a Potential Hydrogen Source for Reduction Reactions Enabled by a Commercial Pt/C Catalyst

Natte, Kishore (2023) Methanol as a Potential Hydrogen Source for Reduction Reactions Enabled by a Commercial Pt/C Catalyst. Journal of Organic Chemistry, 88 (4). pp. 2245-2259. ISSN 0022-3263

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Abstract

Catalytic reduction reactions using methanol as a transfer hydrogenating agent is gaining significant attention because this simple alcohol is inexpensive and produced on a bulk scale. Herein, we report the catalytic utilization of methanol as a hydrogen source for the reduction of different functional organic compounds such as nitroarenes, olefins, and carbonyl compounds. The key to the success of this transformation is the use of a commercially available Pt/C catalyst, which enabled the transfer hydrogenation of a series of simple and functionalized nitroarenes-to-anilines, alkenes-to-alkanes, and aldehydes-to-alcohols using methanol as both the solvent and hydrogen donor. The practicability of this Pt-based protocol is showcased by demonstrating catalyst recycling and reusability as well as reaction upscaling. In addition, the Pt/C catalytic system was also adaptable for the N-methylation and N-alkylation of anilines via the borrowing hydrogen process. This work provides a simple and flexible approach to prepare a variety of value-added products from readily available methanol, Pt/C, and other starting materials.

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IITH Creators:

IITH Creators	ORCiD
Natte, Kishore	https://orcid.org/0000-0001-8557-1969

Item Type:

Article

Uncontrolled Keywords:

alkylation; Article; catalyst; chemical reaction kinetics; dehalogenation; hydrogenation; nucleophilicity; oxidation reduction reaction; polymerization; protein methylation; reaction optimization; substitution reaction; synthesis; Catalytic reduction; Functional organic compounds; Hydrogen sources; Nitroarenes; Potential hydrogens; Pt/C catalysts; Reduction reaction; Simple alcohols; Simple++; carbonyl derivative; hydrogen; methanol; Alkylation; Aniline; Catalysts; Hydrogen; Olefins; Organic solvents; Reusability; Methanol

Subjects:

Chemistry > Electrochemistry
Chemistry

Divisions:

Department of Chemistry

Depositing User:

Mr Nigam Prasad Bisoyi

Date Deposited:

22 Aug 2023 05:31

Last Modified:

22 Aug 2023 05:31

URI:

http://raiithold.iith.ac.in/id/eprint/11589