One-pot synthesis of indenobenzofurans via tandem Michael addition-elimination and palladium-catalysed C-H activation

Muthyala, Ramaiah and Naik, Vijaykumar and Khan, Faiz Ahmed (2022) One-pot synthesis of indenobenzofurans via tandem Michael addition-elimination and palladium-catalysed C-H activation. Arkivoc, 2022 (6). pp. 66-80. ISSN 1551-7012

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Abstract

A tandem, one-pot reaction of 2,3-dibromoindenone with phenols is reported, which provides a straightforward approach to accomplish structurally diverse indenobenzofurans in excellent yields. Besides, the control experiments revealed that reaction proceeds through a two-step sequence via an Intermolecular Michael addition-elimination reaction, which enables the C-O bond formation, followed by palladium-catalyzed intramolecular C-C bond formation through C-H activation. Significantly, this protocol offers a convenient approach to synthesize the diverse tetracyclic indenobenzofurans.

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IITH Creators:	IITH Creators ORCiD Khan, Faiz Ahmed UNSPECIFIED
Item Type:	Article
Additional Information:	We gratefully acknowledge DST and CSIR for financial support. Vijaykumar thanks CSIR for a senior research fellowship.
Uncontrolled Keywords:	DESIGN,DERIVATIVES,EFFICIENT
Subjects:	Chemistry
Divisions:	Department of Chemistry
Depositing User:	. LibTrainee 2021
Date Deposited:	22 Nov 2022 09:00
Last Modified:	22 Nov 2022 09:00
URI:	http://raiithold.iith.ac.in/id/eprint/11374
Publisher URL:	http://doi.org/10.24820/ark.5550190.p011.870
OA policy:	https://v2.sherpa.ac.uk/id/publication/27178
Related URLs:	Author Google Scholar

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