Advances in Nanotechnology for Cancer Immunoprevention and Immunotherapy: A Review

Koyande, Navami Prabhakar and Srivastava, Rupali and Padmakumar, Ananya and Rengan, Aravind Kumar (2022) Advances in Nanotechnology for Cancer Immunoprevention and Immunotherapy: A Review. MDPI.

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Abstract

One of the most effective cancer therapies, cancer immunotherapy has produced outstanding outcomes in the field of cancer treatment. However, the cost is excessive, which limits its applicability. A smart way to address this issue would be to apply the knowledge gained through immunotherapy to develop strategies for the immunoprevention of cancer. The use of cancer vaccines is one of the most popular methods of immunoprevention. This paper reviews the technologies and processes that support the advantages of cancer immunoprevention over traditional cancer immunotherapies. Nanoparticle drug delivery systems and nanoparticle-based nano-vaccines have been employed in the past for cancer immunotherapy. This paper outlines numerous immunoprevention strategies and how nanotechnology can be applied in immunoprevention. To comprehend the non-clinical and clinical evaluation of these cancer vaccines through clinical studies is essential for acceptance of the vaccines. © 2022 by the authors.

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IITH Creators:

IITH Creators	ORCiD
Rengan, Aravind Kumar	https://orcid.org/0000-0003-3994-6760

Item Type:

Other

Additional Information:

The study was supported by DBT (No. DBT/CE/F064/2020-21/G307), MoE IMPRINT (4291), ICMR (No. 35/1/2020-ia/Nano/BMS), DST-Inspire (No. DST/INSPIRE/04/2015/000377), DST-AMT (No. DST/TDT/AMT/2017/227), SERB-CRG (CRG/2020/005069) grants, ICMR-CoE grant, IITH/BME/SOCH3 grant and IITH’s seed grant.

Uncontrolled Keywords:

cancer immunotherapy; cancer vaccines; clinical trials; immunomodulation; tumor antigens

Subjects:

Biomedical Engineering

Divisions:

Department of Biomedical Engineering

Depositing User:

. LibTrainee 2021

Date Deposited:

11 Nov 2022 13:21

Last Modified:

11 Nov 2022 13:21