Polydopamine nanocomposites and their biomedical applications: A review

Chinchulkar, Shubham Arunrao and Patra, Paloma and Dehariya, Dheeraj and Yu, Aimin and Rengan, Aravind Kumar (2022) Polydopamine nanocomposites and their biomedical applications: A review. WILEY.

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Abstract

Polydopamine (PDA) is the end product of the dopamine monomer's self-oxidation polymerization process. PDA is gaining popularity in diagnostic and therapeutic purposes because of its unique properties like excellent biocompatibility, biodegradability, surface functionalization, adhesion, and photothermal, which can help in various biomedical applications. Many researchers have been working on polydopamine nanocomposites in recent years. PDA has been used to modify various structures, such as metal nanoparticles, in order to improve the nanosystem's stability and applicability. This review attempts to cover extremely recent works from 2018 to the present in light of recent developments in PDA nanocomposites. The development of novel PDA nanocomposites for therapeutic applications, such as PDA-metal, PDA-drug, PDA-photosensitizers, and PDA-biomolecules, has been covered in this review. The multiple biomedical applications highlighted in this review include the treatment of cancer, antimicrobial infections, and neurological disorders, as well as wound healing and biosensing. This review will not only help the new researcher to build their base but also for experts to extend their views in this field.

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IITH Creators:

IITH Creators	ORCiD
Rengan, Aravind Kumar	https://orcid.org/0000-0003-3994-6760

Item Type:

Other

Additional Information:

The authors would like to thank Dept. of Science & Technology (DST), Dept. of Biotechnology (DBT), Ministry of Human Resources & Development (MHRD), Govt. of India for funding the following projects DSTInspire (DST/INSPIRE/04/2015/000377), DST-AMT (DST/TDT/AMT/2017/227), CRG/2020/005069, IITH ID BME/MSME grant, DBT BIRAC (BIRAC/IKP0866/BIG14/190) and MoE IMPRINT (4291). Author SAC would like to thank DBT-BIRAC and IITHSUT JDP fellowship for funding. Author DD would like to thank Council of scientific and industrial research (CSIR) for fun; CSIR; MoE PMRF, Grant/Award Number: 2001697; IITHSUT JDP; MoE IMPRINT, Grant/Award Number: 4291; DBT-BIRAC, Grant/Award Number: BIRAC/IKP0866/BIG-14/190; IITH ID BME/MSME; DST-AMT, Grant/Award Number: DST/TDT/AMT/2017/227; DSTInspire, Grant/Award Number: DST/INSPIRE/04/2015/000377; Ministry of Human Resources & Development; Department of Biotechnology; Department of Science & Technology, Grant/Award Number: CRG/2020/005069

Uncontrolled Keywords:

OPTICAL-PROPERTIES,SURFACE-CHEMISTRY,INDOCYANINE GREEN

Subjects:

Biomedical Engineering

Divisions:

Department of Biomedical Engineering

Depositing User:

. LibTrainee 2021

Date Deposited:

17 Sep 2022 10:46

Last Modified:

17 Sep 2022 10:46