A TUNABLE DECELLULARIZED LIVER-BASED HYBRID BIOINK

Khati, V. and Ramachandraiah, H. and Gaudenzi, G. and Pati, Falguni and et al, . (2021) A TUNABLE DECELLULARIZED LIVER-BASED HYBRID BIOINK. In: 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021, 10 October 2021through 14 October 2021, Palm Springs, Virtual.

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Abstract

Decellularized extracellular matrix is a tissue-specific biomaterial that recapitulates the complexity of the inherent tissue environment to elicit cellular response. Here, a multi-material decellularized liver (dLM)-based bioink with gelatin is developed and polyethylene glycol crosslinking is used to enhance the viscoelasticity of the dLM. We evaluated the necessity of a post-printing secondary cross-linker mushroom tyrosinase to improve robustness and long term stability. We further demonstrate it's biocompatibility using liver specific gene analysis of HepG2 cells. © 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.

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IITH Creators:	IITH Creators ORCiD Pati, Falguni http://orcid.org/0000-0002-3588-1800
Item Type:	Conference or Workshop Item (Paper)
Uncontrolled Keywords:	bioink, decellularization, dLM, SVA-PEG-SVA, tyrosinase, viscoelastic
Subjects:	Biomedical Engineering
Divisions:	Department of Biomedical Engineering
Depositing User:	. LibTrainee 2021
Date Deposited:	08 Sep 2022 12:09
Last Modified:	08 Sep 2022 12:09
URI:	http://raiithold.iith.ac.in/id/eprint/10484
Publisher URL:
Related URLs:	Author Google Scholar

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